Scotland coach Craig Levein said: "I am sure he will be an asset to our squad should he be selected.
"But, at this stage, I do not want to say too much more other than his goalscoring record speaks for itself."
Scotland's attacking options have been dealt a blow with the news that James McFadden will be out for several months with a knee injury.
And, with Kris Boyd having netted only once this season and struggling to get into the Middlesbrough team, 24-year-old Mackie may be added to Levein's player pool.
Jamie is a player we have been aware of for some time and we have monitored his progress at QPR
Scotland coach Craig Levein
The former Exeter City player joined QPR from Plymouth Argyle in the summer for £150,000 and is understood to be open to the idea of playing for both Scotland and England.
"Jamie is a player we have been aware of for some time and we have monitored his progress at QPR," added Levein.
"He has had a tremendous start to the season and is a striker in form, which is a significant factor in us taking a closer look at him with a view to the forthcoming double header.
"I will not name the squad until Thursday so don't want to start speculating about this player or that player.
"But Jamie's name has now appeared in the media and he is one who is eligible to play for Scotland."
Source: BBC Sport
Source: BBC Sport